Gene

pex6

ID
ZDB-GENE-081104-252
Name
peroxisomal biogenesis factor 6
Symbol
pex6 Nomenclature History
Previous Names
  • si:ch73-197b13.2
  • si:ch73-197b13.3
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have ATPase activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to localize to cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in Heimler syndrome 2; peroxisomal biogenesis disorder; and peroxisome biogenesis disorder 4A. Orthologous to human PEX6 (peroxisomal biogenesis factor 6).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pex6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Heimler syndrome 2 Alliance Heimler syndrome 2 616617
peroxisome biogenesis disorder 4A Alliance Peroxisome biogenesis disorder 4A (Zellweger) 614862
Peroxisome biogenesis disorder 4B 614863
Associated With pex6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003960 ATPase, AAA-type, conserved site
Domain IPR003593 AAA+ ATPase domain
Domain IPR003959 ATPase, AAA-type, core
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain ATPase, AAA-type, conserved site ATPase, AAA-type, core P-loop containing nucleoside triphosphate hydrolase
UniProtKB:F6P662 1028
UniProtKB:F1QMB0 1071
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations