Gene
pex6
- ID
- ZDB-GENE-081104-252
- Name
- peroxisomal biogenesis factor 6
- Symbol
- pex6 Nomenclature History
- Previous Names
-
- si:ch73-197b13.2
- si:ch73-197b13.3
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have ATPase activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to localize to cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in Heimler syndrome 2; peroxisomal biogenesis disorder; and peroxisome biogenesis disorder 4A. Orthologous to human PEX6 (peroxisomal biogenesis factor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Heimler syndrome 2 | Alliance | Heimler syndrome 2 | 616617 |
| peroxisome biogenesis disorder 4A | Alliance | Peroxisome biogenesis disorder 4A (Zellweger) | 614862 |
| Peroxisome biogenesis disorder 4B | Alliance | Peroxisome biogenesis disorder 4B | 614863 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003960 | ATPase, AAA-type, conserved site |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR041569 | AAA ATPase, AAA+ lid domain |
| Domain | IPR047533 | Peroxisomal biogenesis factor 6, second ATPase domain |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | AAA ATPase, AAA+ lid domain | AAA+ ATPase domain | ATPase, AAA-type, conserved site | ATPase, AAA-type, core | Peroxisomal biogenesis factor 6, second ATPase domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QMB0
|
1071 | ||||||
|
UniProtKB:A0A8M9PSM5
|
564 | ||||||
|
UniProtKB:A0A8M9P4U9
|
507 |
Interactions and Pathways
No data available
Plasmids
No data available