ZFIN ID: ZDB-GENE-081028-48
Gene Name: T, brachyury homolog b
Gene Symbol: tb
Previous Names: bra (1), brachyury (1), no tail b, ntlb, si:ch211-130h14.5
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from Martin et al., 2008
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Pharyngula:Prim-5 (24.0h-30.0h)
  margin, mesoderm, notochord, tail bud (all 5) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Targeting reagents: MO1-tb (1), MO2-tb (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tb HUMAN ORTHOLOG 
Disease Ontology Term OMIM Term OMIM Phenotype ID
Sacral agenesis with vertebral anomalies 615709
{Neural tube defects, susceptibility to} 182940
GENE ONTOLOGY 
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001699 (1)
  • InterPro:IPR002070 (1)
  • InterPro:IPR008967 (1)
  • InterPro:IPR018186 (1)
  • PROSITE:PS01264 (1)
  • PROSITE:PS01283 (1)
  • PROSITE:PS50252 (1)
  • Pfam:PF00907 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tb-001 (1) 1583
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tb No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    tbContained in: [BAC] CH211-130H14 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_001343597 (1) 2496bp
    Genomic GenBank:CR854838 (1) 154065bp
    Select Tool
    Polypeptide UniProtKB:X1WGE3 (1) 424aa
    Sequence Information (all 8)
    OTHER tb GENE PAGES 
  • Gene:100004296 (1)
  • VEGA:OTTDARG00000029381 (1)
  • Ensembl(GRCz10):ENSDARG00000039806 (1)
  • ORTHOLOGY for tb (Chr: 13) 
    Species Symbol Chromosome Accession # Evidence
    Human T 6
  • Gene:6862
  • OMIM:601397
  • HGNC:11515
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse T 17
  • MGI:98472
  • Gene:20997
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (18)