Gene
htra2-4
- ID
- ZDB-GENE-081028-23
- Name
- HtrA serine peptidase 2-4
- Symbol
- htra2-4 Nomenclature History
- Previous Names
-
- si:dkey-19p15.4
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable serine-type endopeptidase activity. Predicted to act upstream of or within proteolysis. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 8; Parkinson's disease; and motor neuron disease. Orthologous to human HTRA2 (HtrA serine peptidase 2).
- Genome Resources
- Note
-
Was previously associated with ENSDARG00000068667 which is now obsolete in Ensembl. Maps to Gene ID: 100137109
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | PDZ domain | PDZ domain 6 | PDZ superfamily | Peptidase S1C | Peptidase S1, PA clan | Serine proteases, trypsin domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A9JSY1 | InterPro | 200 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:174193-206
(1)
|
Ensembl | 1,238 nt | ||
| mRNA |
zgc:174193-207
(1)
|
Ensembl | 1,208 nt |
Interactions and Pathways
No data available
Plasmids
No data available