ZFIN ID: ZDB-GENE-081027-5
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Gene Name: teneurin transmembrane protein 2
Gene Symbol: tenm2    Nomenclature History

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Previous Name: si:dkey-34l15.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have cell adhesion molecule binding activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and neuron development. Predicted to localize to the neuron projection. Orthologous to human TENM2 (teneurin transmembrane protein 2).
Genome Resources: Alliance (1),  Gene:563197 (1),  Ensembl(GRCz11):ENSDARG00000037122 (2)
GENE EXPRESSION
All Expression Data: 5 figures from Cheung et al., 2019
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1449 Point Mutation Unknown Premature Stop ENU
sa1714 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa11224 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa13488 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa15917 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa17807 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa18320 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa22492 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa22493 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa22494 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa22495 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa22496 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa22497 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa22498 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa31988 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa35702 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa42403 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tenm2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tenm2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Cellular Component integral component of membrane (more)
    Molecular Function cell adhesion molecule binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000742 EGF-like domain
    Repeat IPR006530 YD repeat
    Homologous_superfamily IPR008969 Carboxypeptidase-like, regulatory domain superfamily
    Domain IPR009471 Teneurin intracellular, N-terminal
    Homologous_superfamily IPR011042 Six-bladed beta-propeller, TolB-like
    Conserved_site IPR013032 EGF-like, conserved site
    Domain IPR013111 EGF-like domain, extracellular
    Domain IPR022385 Rhs repeat-associated core
    Family IPR027689 Teneurin-2/3
    Domain IPR028916 Tox-GHH domain
    Repeat IPR031325 RHS repeat
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tenm2-204 (1)    Ensembl 1143
    Select Tool
    tenm2-206 (1)    Ensembl 9061
    Select Tool
    Browsers: NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tenm2 No data available
    MARKER RELATIONSHIPS
    tenm2 Contained in: [BAC] DKEY-15G24 (1) (order this), DKEY-34L15 (1) (order this), DKEY-48C14 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009291154 (1)
    Select Tool
    Genomic GenBank:CR847533 (1) 234870 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0H2UKW9 (1) 2612 aa
    Select Tool
    Sequence Information (all 36)
    ORTHOLOGY for tenm2 ( Chr: 14 )
    CITATIONS (17)