Gene

maptb

ID
ZDB-GENE-081027-2
Name
microtubule-associated protein tau b
Symbol
maptb Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization and neuron projection development. Predicted to localize to neuron projection. Human ortholog(s) of this gene implicated in dementia (multiple); neurodegenerative disease (multiple); progressive supranuclear palsy; and temporal lobe epilepsy. Is expressed in nervous system; shield; spinal cord neural tube; and trigeminal placode. Orthologous to human MAPT (microtubule associated protein tau).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With maptb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
frontotemporal dementia Alliance Dementia, frontotemporal, with or without parkinsonism 600274
late onset Parkinson's disease Alliance {Parkinson disease, susceptibility to} 168600
Pick's disease Alliance Pick disease 172700
progressive supranuclear palsy Alliance Supranuclear palsy, progressive 601104
Supranuclear palsy, progressive atypical 260540
Associated With maptb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR030797 Microtubule-associated protein 2
Repeat IPR001084 Microtubule associated protein, tubulin-binding repeat
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations