Gene

acd

ID
ZDB-GENE-081022-45
Name
ACD shelterin complex subunit and telomerase recruitment factor
Symbol
acd Nomenclature History
Previous Names
  • tpp1 (1)
  • zfTPP1 (1)
  • zgc:193816
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits telomeric DNA binding activity. Involved in heart development and negative regulation of apoptotic process. Predicted to localize to shelterin complex. Human ortholog(s) of this gene implicated in autosomal dominant dyskeratosis congenita 6. Orthologous to human ACD (ACD shelterin complex subunit and telomerase recruitment factor).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Xie et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acd Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant dyskeratosis congenita 6 Alliance ?Dyskeratosis congenita, autosomal dominant 6 616553
autosomal dominant dyskeratosis congenita 6 Alliance ?Dyskeratosis congenita, autosomal recessive 7 616553
Associated With acd Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR028631 Adrenocortical dysplasia protein
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations