ZFIN ID: ZDB-GENE-081022-41
Gene Name: adenosine A2a receptor b
Gene Symbol: adora2ab    Nomenclature History

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Previous Names: a2ab (1), adora2a.2 (1), zgc:193802, zgc:193822

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have G protein-coupled adenosine receptor activity. Predicted to be involved in adenosine receptor signaling pathway. Predicted to localize to the integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in asthma. Is expressed in several structures, including central nervous system; interrenal primordium; margin; tail bud; and yolk syncytial layer. Orthologous to human ADORA2A (adenosine A2a receptor).
Genome Resources: Alliance (1),  Gene:566118 (1),  Ensembl(GRCz11):ENSDARG00000058488 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
uva6 Small Deletion Unknown Unknown
uva7 Indel Unknown Unknown
uva9 Small Deletion Unknown Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-adora2ab 1
MO1-adora2ab N/A 1
MO2-adora2ab N/A 1
DISEASE ASSOCIATED WITH adora2ab HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH adora2ab VIA EXPERIMENTAL MODELS No data available
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR001513 Adenosine A2A receptor
Family IPR001634 Adenosine receptor
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA adora2ab-201 (1)    Ensembl 1528
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM adora2ab No data available
MARKER RELATIONSHIPS
adora2ab Contained in: [BAC] CH73-68C19 (1)
adora2ab Encodes: [cDNA] MGC:193802 (1), MGC:193822 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001040036 (1)
Genomic GenBank:CU570693 (1) 52530 nt
Select Tool
Polypeptide UniProtKB:Q29ST5 (1) 447 aa
Sequence Information (all 17)
ORTHOLOGY for adora2ab ( Chr: 21 )
CITATIONS (31)