ZFIN ID: ZDB-GENE-081022-39
Gene Name: polyhomeotic homolog 1
Gene Symbol: phc1    Nomenclature History

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Previous Name: zgc:193796

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have zinc ion binding activity. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 11. Orthologous to human PHC1 (polyhomeotic homolog 1).
Genome Resources: Alliance (1),  Gene:403008 (1),  Ensembl(GRCz11):ENSDARG00000002971 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH phc1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary autosomal recessive microcephaly 11 Alliance ?Microcephaly 11, primary, autosomal recessive 615414
DISEASE ASSOCIATED WITH phc1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process biological_process (more)
Cellular Component nucleus (more)
Molecular Function metal ion binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001660 Sterile alpha motif domain
Domain IPR012313 Zinc finger, FCS-type
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR038603 FCS-type zinc finger superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA phc1-201 (1)    Ensembl 4194
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM phc1 No data available
MARKER RELATIONSHIPS
phc1 Contained in: [BAC] DKEY-40M6 (1) (order this)
[Fosmid] CH1073-29K5 (1)
phc1 Encodes: [cDNA] MGC:193796 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_205707 (1) 3909 bp
Genomic GenBank:CR854927 (1) 217399 bp Blast at MegaBLAST
Polypeptide UniProtKB:E7F4T8 (1) 901 aa
Sequence Information (all 20)
ORTHOLOGY for phc1 ( Chr: 16 )
CITATIONS (18)