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ZIRC
ZFIN ID: ZDB-GENE-081022-110
Gene Name: cyclin-dependent kinase-like 5
Gene Symbol: cdkl5
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:194395

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(Including Attributions)
Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in positive regulation of axon extension; protein phosphorylation; and regulation of dendrite development.  ...
GENE EXPRESSION
All Expression Data: Fig. 6 from Katayama et al., 2016
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16950 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa21938 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24892 Point Mutation Unknown Splice Site ENU
    sa35110 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35111 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cdkl5 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    early infantile epileptic encephalopathy 2 Epileptic encephalopathy, early infantile, 2 300672
    DISEASE ASSOCIATED WITH cdkl5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function cyclin-dependent protein serine/threonine kinase activity (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cdkl5-201 (1) 3936
    cdkl5-202 (1) 3479
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cdkl5 No data available
    MARKER RELATIONSHIPS
    cdkl5Contained in: [BAC] DKEY-163F14 (1) (order this)
    cdkl5Encodes: [cDNA] MGC:194395 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001145768 (1) 3427bp
    Genomic GenBank:CR790368 (1) 160194bp
    Select Tool
    Polypeptide UniProtKB:B9X2H6 (1) 1080aa
    Sequence Clusters UniGene:90479 (1)
    Sequence Information (all 24)
    ORTHOLOGY for cdkl5 (Chr: 11)
    CITATIONS (19)