ZFIN ID: ZDB-GENE-081003-3
Gene Name: prospero homeobox 2
Gene Symbol: prox2    Nomenclature History

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Previous Name: prox1-like (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including gonad; hindbrain neural keel; immature eye; liver; and nervous system. Orthologous to human PROX2 (prospero homeobox 2).
Genome Resources: Alliance (1),  Gene:100003863 (1),  Ensembl(GRCz11):ENSDARG00000041952 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH prox2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH prox2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA prox2-201 (1)    Ensembl 2432
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM prox2 No data available
MARKER RELATIONSHIPS
prox2 Contained in: [BAC] CH211-173A9 (1), DKEY-21D17 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001128292 (1) 2435 nt
Genomic GenBank:AL935141 (1) 136178 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IEJ0 (1) 583 aa
Sequence Information (all 11)
ORTHOLOGY for prox2 ( Chr: 17 )
CITATIONS (16)