Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-080917-49
Gene Name: WNK lysine deficient protein kinase 1a
Gene Symbol: wnk1a
Previous Name: im:7165255
Location: Chr: 25   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7165255]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
  whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa16044, sa16394
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Neuropathy, hereditary sensory and autonomic, type II 201300
Pseudohypoaldosteronism, type IIC 614492
GENE ONTOLOGY
Ontology GO Term
Biological Process protein phosphorylation (more)
Cellular Component cellular_component (more)
Molecular Function ATP binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR024678 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • Pfam:PF12202 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wnk1a-001 (1) 8103
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM wnk1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    wnk1a Contained in: [BAC] CH211-249B21 (1) (order this)
    wnk1a Encodes: [EST] IMAGE:7165255 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_002666846 (1) 7405 bp
    Genomic GenBank:CR354611 (1) 81016 bp
    Select Tool
    Polypeptide UniProtKB:E7F2F9 (1) 1606 aa
    Sequence Clusters UniGene:156842 (1)
    Sequence Information (all 7)
    OTHER wnk1a GENE PAGES
  • Gene:100318736 (1)
  • VEGA:OTTDARG00000039406 (1)
  • Ensembl(Zv9):ENSDARG00000078992 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish wnk1a 25  
    Human WNK1 12 (12p13.3)
  • OMIM:605232
  • Gene:65125
  • Mouse Wnk1 6 ( 56.86 cM)
  • MGI:2442092
  • Gene:232341
  • Orthology Details
    CITATIONS (11)