Gene

plxnb2b

ID
ZDB-GENE-080902-1
Name
plexin b2b
Symbol
plxnb2b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable semaphorin receptor activity. Predicted to be involved in several processes, including positive regulation of axonogenesis; regulation of GTPase activity; and semaphorin-plexin signaling pathway involved in axon guidance. Predicted to act upstream of or within semaphorin-plexin signaling pathway. Predicted to be located in membrane. Predicted to be part of semaphorin receptor complex. Predicted to be active in plasma membrane. Is expressed in head; nervous system; otic vesicle; and pectoral fin. Orthologous to human PLXNB2 (plexin B2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Perälä et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plxnb2b Human Ortholog
No data available
Associated With plxnb2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001627 Sema domain
Domain IPR002909 IPT domain
Domain IPR013548 Plexin, cytoplasmic RasGAP domain
Domain IPR016201 PSI domain
Domain IPR041019 Plexin, TIG domain 1
Family IPR031148 Plexin family
Homologous_superfamily IPR008936 Rho GTPase activation protein
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR014756 Immunoglobulin E-set
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036352 Sema domain superfamily
Repeat IPR002165 Plexin repeat
Domain Details Per Protein
Protein Length Immunoglobulin E-set Immunoglobulin-like fold IPT domain Plexin, cytoplasmic RasGAP domain Plexin family Plexin repeat Plexin, TIG domain 1 PSI domain Rho GTPase activation protein Sema domain Sema domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:E7FGY1 1846
UniProtKB:E3NZJ2 1811
UniProtKB:E3NZJ1 1847
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations