Gene

gabra6b

ID
ZDB-GENE-080815-1
Name
gamma-aminobutyric acid type A receptor subunit alpha6b
Symbol
gabra6b Nomenclature History
Previous Names
  • gabara6 (1)
  • gabra6 (1)
  • GABA receptor alpha 6 subunit (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to contribute to GABA-A receptor activity; benzodiazepine receptor activity; and chloride channel activity. Predicted to be involved in several processes, including GABAergic synaptic transmission; chloride transmembrane transport; and gamma-aminobutyric acid signaling pathway. Predicted to localize to several cellular components, including GABA-A receptor complex; dendrite membrane; and postsynapse. Is expressed in cerebellum; eye; and olfactory bulb. Orthologous to human GABRA6 (gamma-aminobutyric acid type A receptor subunit alpha6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gabra6b Human Ortholog
No data available
Associated With gabra6b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018000 Neurotransmitter-gated ion-channel, conserved site
Domain IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
Domain IPR006202 Neurotransmitter-gated ion-channel ligand-binding domain
Domain IPR047024 Gamma-aminobutyric acid receptor subunit alpha 1-6, transmembrane domain
Family IPR001390 Gamma-aminobutyric-acid A receptor, alpha subunit
Family IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
Family IPR006201 Neurotransmitter-gated ion-channel
Homologous_superfamily IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamily
Homologous_superfamily IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Homologous_superfamily IPR038050 Neuronal acetylcholine receptor
Domain Details Per Protein
Protein Length Gamma-aminobutyric-acid A receptor, alpha subunit Gamma-aminobutyric acid A receptor/Glycine receptor alpha Gamma-aminobutyric acid receptor subunit alpha 1-6, transmembrane domain Neuronal acetylcholine receptor Neurotransmitter-gated ion-channel Neurotransmitter-gated ion-channel, conserved site Neurotransmitter-gated ion-channel ligand-binding domain Neurotransmitter-gated ion-channel ligand-binding domain superfamily Neurotransmitter-gated ion-channel transmembrane domain Neurotransmitter-gated ion-channel transmembrane domain superfamily
UniProtKB:F1QGW0 444
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations