ZFIN ID: ZDB-GENE-080804-1
Gene Name: protocadherin 18b
Gene Symbol: pcdh18b    Nomenclature History

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Previous Names: pcdh18 (1), fj19f12, wu:fj19f12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Involved in neuron projection morphogenesis. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including head; nervous system; neural rod; pectoral fin bud; and spinal cord neural tube. Orthologous to human PCDH18 (protocadherin 18).
Genome Resources: Alliance (1),  Gene:562031 (1),  Ensembl(GRCz11):ENSDARG00000052494 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh513 Small Deletion Unknown Unknown CRISPR
sa7396 Point Mutation Unknown Missense ENU
sa10255 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22533 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pcdh18b N/A 1
    MO2-pcdh18b N/A 1
    MO3-pcdh18b N/A 1
    MO4-pcdh18b N/A 1
    DISEASE ASSOCIATED WITH pcdh18b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pcdh18b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neuron projection morphogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function protein binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pcdh18b-201 (1)    Ensembl 4372
    pcdh18b-202 (1)    Ensembl 3645
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pcdh18b No data available
    MARKER RELATIONSHIPS
    pcdh18b Contained in: [BAC] CH211-154P8, DKEY-86P22 (order this)
    pcdh18b Encodes: [EST] fj19f12
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001115099 (1) 3689 nt
    Genomic GenBank:BX537109 (1) 231134 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8RMH2 (1) 1150 aa
    Sequence Information (all 17)
    ORTHOLOGY for pcdh18b ( Chr: 14 )
    CITATIONS (23)