ZFIN ID: ZDB-GENE-080725-1
Gene Name: SRY (sex determining region Y)-box 18
Gene Symbol: sox18
Sequence Ontology ID : SO:0000704

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Previous Name: si:ch211-235f6.2 (1)

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 8 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Pharyngula:Prim-25 (36.0h-42.0h)
  angioblastic mesenchymal cell, anterior lateral plate mesoderm, axial blood vessel, axial vasculature (all 23) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu10320 Insertion Unknown Unknown TALEN
sa12315 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-sox18 (1), MO2-sox18 (1), MO3-sox18 (1), MO4-sox18 (1), MO5-sox18 (1) (all 8) expand
    PHENOTYPE
    Data: 4 figures from 2 publications
    Observed in: dorsal aorta blood vessel endothelium, posterior cardinal vein blood vessel endothelium, posterior cardinal vein vascular lymphangioblast, posterior cardinal vein vascular sprouts (all 6) expand
    DISEASE ASSOCIATED WITH sox18 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 137940
    Hypotrichosis-lymphedema-telangiectasia syndrome 607823
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process artery development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR009071 (1)
  • InterPro:IPR021934 (1)
  • InterPro:IPR033392 (1)
  • PROSITE:PS50118 (1)
  • PROSITE:PS51516 (1)
  • Pfam:PF00505 (1)
  • Pfam:PF12067 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA sox18-001 (1) 1530
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM sox18 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    sox18Contained in: [BAC] CH211-235F6 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_017353772 (1) 3096bp
    Genomic GenBank:CR457456 (1) 146468bp
    Select Tool
    Polypeptide UniProtKB:E7F9I2 (1) 431aa
    Sequence Clusters UniGene:88332 (1)
    Sequence Information (all 9)
    OTHER sox18 GENE PAGES
  • Gene:797246 (1)
  • VEGA:OTTDARG00000030588 (1)
  • Ensembl(GRCz10):ENSDARG00000058598 (1)
  • ORTHOLOGY for sox18 (Chr: 23)
    CITATIONS (32)