ZFIN ID: ZDB-GENE-080724-3
Gene Name: cytochrome P450, family 2, subfamily AA, polypeptide 9
Gene Symbol: cyp2aa9    Nomenclature History

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Previous Name: zgc:195056

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in acute myeloid leukemia; asthma; autoimmune hepatitis; precursor lymphoblastic lymphoma/leukemia; and rhinitis. Orthologous to human CYP2D6 (cytochrome P450 family 2 subfamily D member 6).
Genome Resources: Alliance (1),  Gene:790957 (1),  Ensembl(GRCz11):ENSDARG00000098890 (1)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-cyp2aa3,cyp2aa9 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cyp2aa9 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH cyp2aa9 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component integral component of membrane (more)
Molecular Function heme binding (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Conserved_site IPR017972 Cytochrome P450, conserved site
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA cyp2aa9-201 (1)    Ensembl 1557
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cyp2aa9 No data available
MARKER RELATIONSHIPS
cyp2aa9 Contained in: [BAC] DKEY-12M15 (1) (order this)
cyp2aa9 Contains: [STS] chunp30128
cyp2aa9 Encodes: [cDNA] MGC:195056 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001079851 (1) 1581 bp
Genomic GenBank:CU013526 (1) 111595 bp
Select Tool
Polypeptide UniProtKB:A0A0R4IV56 (1) 499 aa
Sequence Information (all 14)
ORTHOLOGY for cyp2aa9 ( Chr: 23 )
CITATIONS (21)