Gene

trub1

ID

ZDB-GENE-080723-73

Name

TruB pseudouridine (psi) synthase family member 1

Symbol

trub1 Nomenclature History

Previous Names

zgc:195155

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Is predicted to enable pseudouridine synthase activity. Involved in mRNA pseudouridine synthesis and tRNA modification. Acts upstream of or within RNA processing and pseudouridine synthesis. Orthologous to human TRUB1 (TruB pseudouridine synthase family member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UCSC scRNA-seq

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trub1 Human Ortholog

No data available

Associated With trub1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002501	Pseudouridine synthase II, N-terminal
Domain	IPR032819	tRNA pseudouridylate synthase B, C-terminal
Family	IPR014780	tRNA pseudouridine synthase II, TruB
Homologous_superfamily	IPR020103	Pseudouridine synthase, catalytic domain superfamily

Domain Details Per Protein

Protein	Length	Pseudouridine synthase, catalytic domain superfamily	Pseudouridine synthase II, N-terminal	tRNA pseudouridine synthase II, TruB	tRNA pseudouridylate synthase B, C-terminal
UniProtKB:F8W5W3 InterPro	89
UniProtKB:B3DHG0 InterPro	290
UniProtKB:F8W456 InterPro	258
UniProtKB:F8W3T9 InterPro	133

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
aberrant processed transcript	trub1-203 (1) Ensembl	973 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	trub1-201 (1) Ensembl	1197 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	trub1-202 (1) Ensembl	892 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	trub1-204 (1) Ensembl	400 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations