ZFIN ID: ZDB-GENE-080723-32
Gene Name: cholinergic receptor, muscarinic 5a
Gene Symbol: chrm5a    Nomenclature History

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Previous Names: zgc:194865, zgc:194868

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have G protein-coupled acetylcholine receptor activity and G protein-coupled serotonin receptor activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway and chemical synaptic transmission. Predicted to localize to dendrite; integral component of plasma membrane; and synapse. Is expressed in eye. Orthologous to human CHRM5 (cholinergic receptor muscarinic 5).
Genome Resources: Alliance (1),  Gene:553978 (1),  Ensembl(GRCz11):ENSDARG00000099928 (1)
GENE EXPRESSION
All Expression Data: Fig. 2 from Nuckels et al., 2011
Wild-type Stages, Structures: Larval:Days 14-20 (14d-21d, 6.2mm, 10 teeth) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12034 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH chrm5a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH chrm5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process G protein-coupled receptor signaling pathway (more)
    Cellular Component cell junction (more)
    Molecular Function G protein-coupled acetylcholine receptor activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chrm5a No data available
    MARKER RELATIONSHIPS
    chrm5a Encodes: [cDNA] MGC:194865 (1), MGC:194868 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001020803 (1) 1473 nt
    Genomic GenBank:AY039654 (1) 1473 nt
    Polypeptide UniProtKB:B3DJA3 (1) 490 aa
    Sequence Information (all 14)
    ORTHOLOGY for chrm5a ( Chr: 17 )
    CITATIONS (18)