Community Action Needed: Please respond to the NIH RFI
Gene

socs5b

ID
ZDB-GENE-080722-18
Name
suppressor of cytokine signaling 5b
Symbol
socs5b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within several processes, including cell surface receptor signaling pathway; intracellular signal transduction; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of phosphatidylinositol 3-kinase complex. Orthologous to human SOCS5 (suppressor of cytokine signaling 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With socs5b Human Ortholog
No data available
Associated With socs5b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001496 SOCS box domain
Domain IPR022252 SOCS4/SOCS5 domain
Domain IPR037343 SOCS5, SOCS box domain
Homologous_superfamily IPR036036 SOCS box-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length SH2 domain SH2 domain superfamily SOCS4/SOCS5 domain SOCS5, SOCS box domain SOCS box domain SOCS box-like domain superfamily
UniProtKB:B0EVP6 557
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations