Gene

add2

ID
ZDB-GENE-080718-4
Name
adducin 2 (beta)
Symbol
add2 Nomenclature History
Previous Names
  • si:dkey-202n14.5 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity; spectrin binding activity; and structural molecule activity. Predicted to be involved in actin filament bundle assembly and barbed-end actin filament capping. Predicted to localize to cytoskeleton; plasma membrane raft; and postsynaptic density. Is expressed in head. Human ortholog(s) of this gene implicated in IgA glomerulonephritis and hypertension. Orthologous to human ADD2 (adducin 2).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 1 from Tang et al., 2016
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With add2 Human Ortholog
No data available
Associated With add2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001303 Class II aldolase/adducin N-terminal
Family IPR027773 Beta-adducin
Homologous_superfamily IPR036409 Class II aldolase/adducin N-terminal domain superfamily
Domain Details Per Protein
Protein Length Beta-adducin Class II aldolase/adducin N-terminal Class II aldolase/adducin N-terminal domain superfamily
UniProtKB:F1QTE3 669
UniProtKB:F1RBS8 645
UniProtKB:A0A2R8QI45 606
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations