ZFIN ID: ZDB-GENE-080708-1
Gene Name: macrophage migration inhibitory factor
Gene Symbol: mif    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Involved in several processes, including auditory receptor cell development; embryonic morphogenesis; and negative regulation of apoptotic process. Is expressed in several structures, including digestive system; immature eye; nervous system; pectoral fin bud; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in allergic hypersensitivity disease; asthma; cystic fibrosis; lung disease (multiple); and obesity. Orthologous to human MIF (macrophage migration inhibitory factor).
Genome Resources: Alliance (1),  Gene:751093 (1),  Ensembl(GRCz11):ENSDARG00000071336 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019079Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-mif N/A 1
    MO2-mif N/A 1
    MO3-mif N/A 1
    MO4-mif N/A 3
    MO5-mif N/A 1
    MO6-mif N/A 1
    DISEASE ASSOCIATED WITH mif HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    juvenile rheumatoid arthritis Alliance {Rheumatoid arthritis, systemic juvenile, susceptibility to} 604302
    DISEASE ASSOCIATED WITH mif VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process inner ear development (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mif-201 (1)    Ensembl 660
    mif-202 (1)    Ensembl 1129
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mif No data available
    MARKER RELATIONSHIPS
    mif Contained in: [BAC] DKEYP-121D2
    mif Encodes: [cDNA] MGC:198147 (1), MGC:198149 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001043321 (1) 623 nt
    Genomic GenBank:CR855307 (1) 167962 nt
    Select Tool
    Polypeptide UniProtKB:Q0ZBR7 (1) 115 aa
    Sequence Information (all 18)
    ORTHOLOGY for mif ( Chr: 14 )
    CITATIONS (37)