prdm1b

ID

ZDB-GENE-080618-2

Name

PR domain containing 1b, with ZNF domain

Symbol

prdm1b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate commitment and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular developmental process and methylation. Predicted to be active in cytoplasm and nucleus. Is expressed in retina and somite. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung adenocarcinoma. Orthologous to human PRDM1 (PR/SET domain 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With prdm1b Human Ortholog

No data available

Associated With prdm1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001214	SET domain
Domain	IPR013087	Zinc finger C2H2-type
Domain	IPR044413	PRDM1, PR/SET domain
Family	IPR016608	PR domain zinc finger protein 1
Family	IPR050331	Zinc finger
Homologous_superfamily	IPR036236	Zinc finger C2H2 superfamily
Homologous_superfamily	IPR046341	SET domain superfamily