ZFIN ID: ZDB-GENE-080522-1
Gene Name: SET domain containing 1B, histone lysine methyltransferase b
Gene Symbol: setd1bb    Nomenclature History

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Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have RNA binding activity and histone-lysine N-methyltransferase activity. Predicted to be involved in histone H3-K4 methylation. Predicted to localize to the Set1C/COMPASS complex. Orthologous to human SETD1B (SET domain containing 1B, histone lysine methyltransferase).
Genome Resources: Alliance (1),  Gene:571274 (1),  Ensembl(GRCz11):ENSDARG00000077244 (2)
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
PHENOTYPE No data available
DISEASE ASSOCIATED WITH setd1bb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH setd1bb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process histone H3-K4 methylation (more)
Cellular Component Set1C/COMPASS complex (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR001214 SET domain
Domain IPR003616 Post-SET domain
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Family IPR037842 Histone-lysine N-methyltransferase SETD1B
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM setd1bb No data available
MARKER RELATIONSHIPS
setd1bb Contained in: [BAC] DKEY-179C19 (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_009304111 (1)
Genomic GenBank:CR786581 166217 bp
Select Tool
Polypeptide UniProtKB:F1QJJ4 (1) 1319 aa
Sequence Information (all 14)
ORTHOLOGY for setd1bb ( Chr: 8 )
CITATIONS (18)