ZFIN ID: ZDB-GENE-080520-3
Gene Name: lysine (K)-specific methyltransferase 2Ca
Gene Symbol: kmt2ca
Previous Names: mll3a, si:ch211-244o18.1, si:ch211-244o18.2
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa44085 Point Mutation Unknown Unknown ENU
sa44086 Point Mutation Unknown Unknown ENU
Targeting reagents: MO1-kmt2ca (1), MO2-kmt2ca (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH kmt2ca HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process histone H3-K4 methylation (more)
Cellular Component nucleus (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001214 (1)
  • InterPro:IPR001841 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR003888 (1)
  • InterPro:IPR003889 (1)
  • InterPro:IPR009071 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR015722 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51542 (1)
  • PROSITE:PS51543 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF00856 (1)
  • Pfam:PF05964 (1)
  • Pfam:PF05965 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA kmt2ca-001 (1) 17032
    kmt2ca-002 (1) 610
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM kmt2ca No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    kmt2caContained in: [BAC] CH211-232L14 (1) (order this), CH211-244O18 (order this), DKEY-148G10 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005162545 (1) 16823bp
    Genomic GenBank:BX294167 (1) 191302bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IM21 (1) 4954aa
    Sequence Clusters UniGene:105981 (1)
    Sequence Information (all 36)
    OTHER kmt2ca GENE PAGES
  • Gene:560793 (1)
  • VEGA:OTTDARG00000031784 (1)
  • Ensembl(GRCz10):ENSDARG00000079312 (1)
  • ORTHOLOGY for kmt2ca (Chr: 24)
    Species Symbol Chromosome Accession # Evidence
    Human KMT2C 7
  • Gene:58508
  • OMIM:606833
  • HGNC:13726
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Kmt2c 5
  • MGI:2444959
  • Gene:231051
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (15)