ZFIN ID: ZDB-GENE-080519-3
Gene Name: nuclear receptor binding SET domain protein 1a
Gene Symbol: nsd1a
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la019080Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027572Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13619 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-nsd1a (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nsd1a HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute myeloid leukemia Leukemia, acute myeloid 601626
    Beckwith-Wiedemann syndrome Beckwith-Wiedemann syndrome 130650
    Sotos syndrome Sotos syndrome 1 117550
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process methylation (more)
    Cellular Component nucleus (more)
    Molecular Function histone-lysine N-methyltransferase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000313 (1)
  • InterPro:IPR001214 (1)
  • InterPro:IPR001841 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR006560 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50812 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51215 (1)
  • Pfam:PF00855 (1)
  • Pfam:PF00856 (1)
  • EC:2.1.1.43 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nsd1a-001 (1) 10655
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nsd1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    nsd1aContained in: [Fosmid] CH1073-100E22 (1) (order this), CH1073-452F17 (1) (order this), CH1073-527A6 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_678798 (1) 7746bp
    Genomic GenBank:CU659412 (1) 36841bp
    Select Tool
    Polypeptide UniProtKB:F1QA79 (1) 2055aa
    Sequence Clusters UniGene:83733 (1)
    Sequence Information (all 12)
    OTHER nsd1a GENE PAGES 
  • Gene:556086 (1)
  • VEGA:OTTDARG00000034925 (1)
  • Ensembl(GRCz10):ENSDARG00000060016 (1)
  • ORTHOLOGY for nsd1a (Chr: 14) 
    Species Symbol Chromosome Accession # Evidence
    Human NSD1 5
  • Gene:64324
  • OMIM:606681
  • HGNC:14234
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Nsd1 13
  • MGI:1276545
  • Gene:18193
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (21)