ZFIN ID: ZDB-GENE-080519-2
Gene Name: nuclear receptor binding SET domain protein 1b
Gene Symbol: nsd1b
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Blastula:Sphere (4.0h-4.33h)
  whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24006 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30724 Point Mutation Unknown Unknown ENU
    sa37358 Point Mutation Unknown Unknown ENU
    sa43694 Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-nsd1b (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nsd1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute myeloid leukemia Leukemia, acute myeloid 601626
    Beckwith-Wiedemann syndrome Beckwith-Wiedemann syndrome 130650
    Sotos syndrome Sotos syndrome 1 117550
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process methylation (more)
    Cellular Component nucleus (more)
    Molecular Function histone-lysine N-methyltransferase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000313 (1)
  • InterPro:IPR001214 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR006560 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50812 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51215 (1)
  • Pfam:PF00855 (1)
  • Pfam:PF00856 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nsd1b-001 (1) 5720
    ncRNA nsd1b-002 (1) 464
    mRNA nsd1b-003 (1) 906
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nsd1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nsd1bContained in: [BAC] DKEY-13F9 (1) (order this), DKEY-106J22 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005173883 (1) 6697bp
    Genomic GenBank:BX842703 (1) 208780bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q9U9 (1) 1873aa
    Sequence Clusters UniGene:119918 (1)
    Sequence Information (all 26)
    OTHER nsd1b GENE PAGES
  • Gene:564592 (1)
  • VEGA:OTTDARG00000031645 (1)
  • Ensembl(GRCz10):ENSDARG00000060705 (1)
  • ORTHOLOGY for nsd1b (Chr: 21)
    Species Symbol Chromosome Accession # Evidence
    Human NSD1 5
  • Gene:64324
  • OMIM:606681
  • HGNC:14234
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Nsd1 13
  • MGI:1276545
  • Gene:18193
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (14)