ZFIN ID: ZDB-GENE-080519-2
Gene Name: nuclear receptor binding SET domain protein 1b
Gene Symbol: nsd1b
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Blastula:Sphere (4.0h-4.33h)
  whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24006 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa30724 Point Mutation Unknown Premature Stop ENU
    sa37358 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa43693 Point Mutation Unknown Premature Stop ENU
    sa43694 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: MO1-nsd1b (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nsd1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute myeloid leukemia Leukemia, acute myeloid 601626
    Beckwith-Wiedemann syndrome Beckwith-Wiedemann syndrome 130650
    Sotos syndrome Sotos syndrome 1 117550
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process methylation (more)
    Cellular Component nucleus (more)
    Molecular Function histone-lysine N-methyltransferase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000313 (1)
  • InterPro:IPR001214 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR006560 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50812 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51215 (1)
  • Pfam:PF00855 (1)
  • Pfam:PF00856 (1)
  • EC:2.1.1.43 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nsd1b-001 (1) 5720
    ncRNA nsd1b-002 (1) 464
    mRNA nsd1b-003 (1) 906
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nsd1b No data available
    MARKER RELATIONSHIPS
    nsd1bContained in: [BAC] DKEY-13F9 (1) (order this), DKEY-106J22 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005173883 (1) 6859bp
    Genomic GenBank:BX842703 (1) 208780bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q9U9 (1) 1873aa
    Sequence Clusters UniGene:119918 (1)
    Sequence Information (all 23)
    OTHER nsd1b GENE PAGES
  • Alliance (1)
  • Gene:564592 (1)
  • VEGA:OTTDARG00000031645 (1)
  • Ensembl(GRCz10):ENSDARG00000060705 (1)
  • ORTHOLOGY for nsd1b (Chr: 21)
    CITATIONS (18)