Gene

slc18a2

ID
ZDB-GENE-080514-1
Name
solute carrier family 18 member 2
Symbol
slc18a2 Nomenclature History
Previous Names
  • vmat2 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to enable serotonin:sodium symporter activity. Acts upstream of or within swimming behavior. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in synaptic vesicle membrane and terminal bouton. Is expressed in brain and neurons. Used to study anxiety disorder. Human ortholog(s) of this gene implicated in Parkinson's disease and type 1 diabetes mellitus. Orthologous to human SLC18A2 (solute carrier family 18 member A2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc18a2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Parkinsonism-dystonia, infantile, 2 618049
Associated With slc18a2 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR020846 Major facilitator superfamily domain
Family IPR004734 Multidrug resistance protein
Family IPR011701 Major facilitator superfamily
Homologous_superfamily IPR036259 MFS transporter superfamily
Domain Details Per Protein
Protein Length Major facilitator superfamily Major facilitator superfamily domain MFS transporter superfamily Multidrug resistance protein
UniProtKB:Q5CZP4 562
UniProtKB:A0A2R8QMY0 499
UniProtKB:A0A2R8QRE0 450
UniProtKB:F1QVV1 562
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations