Gene
keap1b
- ID
- ZDB-GENE-080508-1
- Name
- kelch-like ECH-associated protein 1b
- Symbol
- keap1b Nomenclature History
- Previous Names
-
- klhl19 (1)
- zgc:171654
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have transcription factor binding activity. Involved in cellular protein metabolic process; cellular response to prostaglandin stimulus; and cellular response to xenobiotic stimulus. Predicted to localize to cytoplasm and inclusion body. Is expressed in several structures, including gill; head; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in gallbladder cancer. Orthologous to human KEAP1 (kelch like ECH associated protein 1).
- Genome Resources
- Note
- None
- All Expression Data
- 1 figure from Li et al., 2008
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000210 | BTB/POZ domain |
| Domain | IPR011705 | BTB/Kelch-associated |
| Family | IPR017096 | BTB-kelch protein |
| Family | IPR030563 | Kelch-like ECH-associated protein 1 |
| Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
| Homologous_superfamily | IPR015915 | Kelch-type beta propeller |
| Repeat | IPR006652 | Kelch repeat type 1 |
Domain Details Per Protein
| Protein | Length | BTB/Kelch-associated | BTB-kelch protein | BTB/POZ domain | Kelch-like ECH-associated protein 1 | Kelch repeat type 1 | Kelch-type beta propeller | SKP1/BTB/POZ domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A2R8Q1W5
|
587 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
keap1b-201
(1)
|
3053 nt | |
| mRNA |
keap1b-202
(1)
|
3059 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl