Gene
cadm2b
- ID
- ZDB-GENE-080506-3
- Name
- cell adhesion molecule 2b
- Symbol
- cadm2b Nomenclature History
- Previous Names
-
- si:ch211-220p9.1
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Acts upstream of or within glial cell development and retina development in camera-type eye. Predicted to be located in plasma membrane. Is expressed in eye; immature eye; and nervous system. Human ortholog(s) of this gene implicated in autism spectrum disorder; malignant astrocytoma; obesity; psoriasis; and type 2 diabetes mellitus. Orthologous to human CADM2 (cell adhesion molecule 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Pietri et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Charlton-Perkins et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR003585 | Neurexin/syndecan/glycophorin C |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Domain | IPR013162 | CD80-like, immunoglobulin C2-set |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | CD80-like, immunoglobulin C2-set | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Immunoglobulin subtype 2 | Immunoglobulin V-set domain | Neurexin/syndecan/glycophorin C |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B4C0 | InterPro | 396 | |||||||||
| UniProtKB:A0A8M2B3K2 | InterPro | 441 | |||||||||
| UniProtKB:A0A8M3B0S3 | InterPro | 400 | |||||||||
| UniProtKB:B0F6R2 | InterPro | 401 | |||||||||
| UniProtKB:A0A8M2B3L3 | InterPro | 440 | |||||||||
| UniProtKB:A0A8M2B3T0 | InterPro | 432 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cadm2b-201
(1)
|
Ensembl | 1,259 nt | ||
| mRNA |
cadm2b-202
(1)
|
Ensembl | 1,119 nt |
Interactions and Pathways
No data available
Plasmids
No data available