Gene

cadm2b

ID

ZDB-GENE-080506-3

Name

cell adhesion molecule 2b

Symbol

cadm2b Nomenclature History

Previous Names

si:ch211-220p9.1

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in astrocytoma; autism spectrum disorder; obesity; psoriasis; and type 2 diabetes mellitus. Is expressed in eye; immature eye; and nervous system. Orthologous to human CADM2 (cell adhesion molecule 2).

Genome Resources

Note

Comparative Information

Expression

All Expression Data

4 figures from Pietri et al., 2008

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Charlton-Perkins et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cadm2b Human Ortholog

No data available

Associated With cadm2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003006	Immunoglobulin/major histocompatibility complex, conserved site
Domain	IPR003585	Neurexin/syndecan/glycophorin C
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Domain	IPR013162	CD80-like, immunoglobulin C2-set
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily