ZFIN ID: ZDB-GENE-080425-5
Gene Name: myosin XVIIIAa
Gene Symbol: myo18aa    Nomenclature History

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Previous Names: myo18b (1), myo18l2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; actin filament binding activity; and motor activity. Involved in Golgi organization; cell-matrix adhesion; and striated muscle cell development. Predicted to localize to myosin complex. Is expressed in somite border. Orthologous to human MYO18A (myosin XVIIIA).
Genome Resources: Alliance (1),  Gene:566880 (1),  Ensembl(GRCz11):ENSDARG00000075752 (2)
GENE EXPRESSION
All Expression Data: Fig. 1 from Cao et al., 2014
Wild-type Stages, Structures: Cleavage:32-cell (1.75h-2.0h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12353 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13591 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14885 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16330 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21785 Point Mutation Unknown Missense, Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34956 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34957 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34958 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41712 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sdu12 Small Deletion Unknown Unknown TALEN
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-myo18aa N/A 2
    TALEN1-myo18aa
    1
    TALEN2-myo18aa 1
    DISEASE ASSOCIATED WITH myo18aa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH myo18aa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell-matrix adhesion (more)
    Cellular Component myosin complex (more)
    Molecular Function actin binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA myo18aa-202 (1)    Ensembl 8585
    ncRNA ottdart00000059962 (1) 539
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM myo18aa No data available
    MARKER RELATIONSHIPS
    myo18aa Contained in: [BAC] DKEY-106A24 (1) (order this), DKEY-263L2 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_690164 (1) 8572 nt
    Genomic GenBank:BX323076 (1) 156437 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4J7R2 (1) 2454 aa
    Sequence Information (all 31)
    ORTHOLOGY for myo18aa ( Chr: 10 )
    CITATIONS (22)