Gene

atp2b3b

ID
ZDB-GENE-080409-2
Name
ATPase plasma membrane Ca2+ transporting 3b
Symbol
atp2b3b Nomenclature History
Previous Names
  • pmca3b (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have PDZ domain binding activity and calcium transmembrane transporter activity, phosphorylative mechanism. Predicted to be involved in regulation of cytosolic calcium ion concentration. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in brain and eye. Human ortholog(s) of this gene implicated in X-linked spinocerebellar ataxia 1 and autosomal recessive nonsyndromic deafness 12. Orthologous to several human genes including ATP2B3 (ATPase plasma membrane Ca2+ transporting 3).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 5 from Liao et al., 2007
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atp2b3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
X-linked spinocerebellar ataxia 1 Alliance ?Spinocerebellar ataxia, X-linked 1 302500
Associated With atp2b3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004014 Cation-transporting P-type ATPase, N-terminal
Domain IPR006068 Cation-transporting P-type ATPase, C-terminal
Domain IPR022141 Plasma membrane calcium transporting P-type ATPase, C-terminal
Family IPR001757 P-type ATPase
Family IPR006408 P-type ATPase, subfamily IIB
Family IPR030325 Plasma membrane calcium-transporting ATPase 3
Homologous_superfamily IPR008250 P-type ATPase, A domain superfamily
Homologous_superfamily IPR023214 HAD superfamily
Homologous_superfamily IPR023298 P-type ATPase, transmembrane domain superfamily
Homologous_superfamily IPR023299 P-type ATPase, cytoplasmic domain N
Homologous_superfamily IPR036412 HAD-like superfamily
PTM IPR018303 P-type ATPase, phosphorylation site
Domain Details Per Protein
Protein Length Cation-transporting P-type ATPase, C-terminal Cation-transporting P-type ATPase, N-terminal HAD-like superfamily HAD superfamily Plasma membrane calcium-transporting ATPase 3 Plasma membrane calcium transporting P-type ATPase, C-terminal P-type ATPase P-type ATPase, A domain superfamily P-type ATPase, cytoplasmic domain N P-type ATPase, phosphorylation site P-type ATPase, subfamily IIB P-type ATPase, transmembrane domain superfamily
UniProtKB:B2CZC0 1174
UniProtKB:A0A286Y8X6 1180
UniProtKB:X1WCG5 1180
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations