Gene
nr1h5
- ID
- ZDB-GENE-080403-3
- Name
- nuclear receptor subfamily 1, group H, member 5
- Symbol
- nr1h5 Nomenclature History
- Previous Names
-
- FXRbeta (1)
- gb:dq017614
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in several processes, including cholesterol homeostasis; negative regulation of inflammatory response; and regulation of transcription by RNA polymerase II. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in liver and yolk syncytial layer.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- dq017614 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR050234 | Nuclear hormone receptor family NR1 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Nuclear hormone receptor | Nuclear hormone receptor family NR1 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2BEQ0 | InterPro | 487 | ||||||
| UniProtKB:B0S5T9 | InterPro | 486 |
Interactions and Pathways
No data available
Plasmids
No data available