ZFIN ID: ZDB-GENE-080403-3
Gene Name: nuclear receptor subfamily 1, group H, member 5
Gene Symbol: nr1h5    Nomenclature History

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Previous Names: FXRbeta (1), gb:dq017614

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have several functions, including RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; nuclear receptor activity; and transcription factor binding activity. Predicted to be involved in several processes, including cholesterol homeostasis; lipid metabolic process; and regulation of transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription regulator complex. Is expressed in liver and yolk syncytial layer.
Genome Resources: Alliance (1),  Gene:557500 (1),  Ensembl(GRCz11):ENSDARG00000031046 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2008 [dq017614]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15588 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21210 Point Mutation Unknown Missense, Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nr1h5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nr1h5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component host cell nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nr1h5-201 (1)    Ensembl 1732
    ncRNA nr1h5-002 (1)    Ensembl 810
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nr1h5 No data available
    MARKER RELATIONSHIPS
    nr1h5 Contained in: [BAC] DKEYP-46C9 (1)
    nr1h5 Encodes: [EST] dq017614 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001123241 (1) 1732 nt
    Genomic GenBank:BX321886 (1) 168093 nt
    Select Tool
    Polypeptide UniProtKB:B0S5T9 (1) 486 aa
    Sequence Information (all 11)
    ORTHOLOGY for nr1h5 ( Chr: 8 )
    CITATIONS (24)