ZFIN is now using GRCz12tu for Genomic Data
Gene
kat2a
- ID
- ZDB-GENE-080403-11
- Name
- K(lysine) acetyltransferase 2A
- Symbol
- kat2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables histone H3K9 acetyltransferase activity. Involved in epigenetic regulation of gene expression; regulation of bone development; and regulation of cartilage development. Acts upstream of or within bone morphogenesis; heart development; and limb development. Predicted to be located in centrosome and nucleus. Predicted to be part of ATAC complex and oxoglutarate dehydrogenase complex. Is expressed in brain; fin; head; heart; and otic vesicle. Orthologous to human KAT2A (lysine acetyltransferase 2A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7156024 (1 image)
- dq017634 (7 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018359 | Bromodomain, conserved site |
| Domain | IPR000182 | GNAT domain |
| Domain | IPR001487 | Bromodomain |
| Domain | IPR009464 | PCAF, N-terminal |
| Family | IPR016376 | Histone acetyltransferase GCN5/PCAF |
| Family | IPR037800 | Histone acetyltransferase GCN5 |
| Homologous_superfamily | IPR016181 | Acyl-CoA N-acyltransferase |
| Homologous_superfamily | IPR036427 | Bromodomain-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Acyl-CoA N-acyltransferase | Bromodomain | Bromodomain, conserved site | Bromodomain-like superfamily | GNAT domain | Histone acetyltransferase GCN5 | Histone acetyltransferase GCN5/PCAF | PCAF, N-terminal |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB13ABI6 | InterPro | 795 | ||||||||
| UniProtKB:A0A0R4IXF6 | InterPro | 795 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers