Gene
erap2
- ID
- ZDB-GENE-080402-6
- Name
- endoplasmic reticulum aminopeptidase 2
- Symbol
- erap2 Nomenclature History
- Previous Names
-
- zgc:172163
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including peptide catabolic process; proteolysis; and regulation of blood pressure. Predicted to localize to cytoplasm and plasma membrane. Orthologous to human ERAP2 (endoplasmic reticulum aminopeptidase 2).
- Genome Resources
- Note
- None
- All Expression Data
- 1 figure from Gao et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR014782 | Peptidase M1, membrane alanine aminopeptidase |
| Domain | IPR024571 | ERAP1-like C-terminal domain |
| Family | IPR001930 | Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase |
| Family | IPR033528 | ERAP2 aminopeptidase |
| Family | IPR034016 | Aminopeptidase N-type |
| Homologous_superfamily | IPR042097 | Aminopeptidase N-like , N-terminal |
Domain Details Per Protein
| Protein | Length | Aminopeptidase N-like , N-terminal | Aminopeptidase N-type | ERAP1-like C-terminal domain | ERAP2 aminopeptidase | Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase | Peptidase M1, membrane alanine aminopeptidase |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B1H1J0
|
931 | ||||||
|
UniProtKB:A0A0R4INQ5
|
932 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl