Gene

erap2

ID
ZDB-GENE-080402-6
Name
endoplasmic reticulum aminopeptidase 2
Symbol
erap2 Nomenclature History
Previous Names
  • zgc:172163
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including peptide catabolic process; proteolysis; and regulation of blood pressure. Predicted to localize to cytoplasm and plasma membrane. Orthologous to human ERAP2 (endoplasmic reticulum aminopeptidase 2).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Gao et al., 2014
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With erap2 Human Ortholog
No data available
Associated With erap2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR014782 Peptidase M1, membrane alanine aminopeptidase
Domain IPR024571 ERAP1-like C-terminal domain
Family IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
Family IPR033528 ERAP2 aminopeptidase
Family IPR034016 Aminopeptidase N-type
Homologous_superfamily IPR042097 Aminopeptidase N-like , N-terminal
Domain Details Per Protein
Protein Length Aminopeptidase N-like , N-terminal Aminopeptidase N-type ERAP1-like C-terminal domain ERAP2 aminopeptidase Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase Peptidase M1, membrane alanine aminopeptidase
UniProtKB:B1H1J0 931
UniProtKB:A0A0R4INQ5 932
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations