Gene
erap2
- ID
- ZDB-GENE-080402-6
- Name
- endoplasmic reticulum aminopeptidase 2
- Symbol
- erap2 Nomenclature History
- Previous Names
-
- zgc:172163
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable metalloaminopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum lumen. Orthologous to human ERAP2 (endoplasmic reticulum aminopeptidase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Gao et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR014782 | Peptidase M1, membrane alanine aminopeptidase |
Domain | IPR024571 | ERAP1-like C-terminal domain |
Domain | IPR045357 | Aminopeptidase N-like , N-terminal domain |
Family | IPR001930 | Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase |
Family | IPR034016 | Aminopeptidase N-type |
Family | IPR050344 | Peptidase M1 family aminopeptidases |
Homologous_superfamily | IPR027268 | Peptidase M4/M1, CTD superfamily |
Homologous_superfamily | IPR042097 | Aminopeptidase N-like , N-terminal domain superfamliy |
Domain Details Per Protein
Protein | Additional Resources | Length | Aminopeptidase N-like , N-terminal domain | Aminopeptidase N-like , N-terminal domain superfamliy | Aminopeptidase N-type | ERAP1-like C-terminal domain | Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase | Peptidase M1 family aminopeptidases | Peptidase M1, membrane alanine aminopeptidase | Peptidase M4/M1, CTD superfamily |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:B1H1J0 | InterPro | 931 | ||||||||
UniProtKB:A0A8M2BCU9 | InterPro | 935 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available