Gene

prkcha

ID
ZDB-GENE-080402-5
Name
protein kinase C, eta, a
Symbol
prkcha Nomenclature History
Previous Names
  • zgc:172124
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in cerebral infarction. Orthologous to human PRKCH (protein kinase C eta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prkcha Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cerebral infarction Alliance {Cerebral infarction, susceptibility to} 601367
Associated With prkcha Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000008 C2 domain
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR017892 Protein kinase, C-terminal
Domain IPR020454 Diacylglycerol/phorbol-ester binding
Family IPR014376 Protein kinase C, delta/epsilon/eta/theta types
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal C2 domain C2 domain superfamily Diacylglycerol/phorbol-ester binding Protein kinase, ATP binding site Protein kinase C, delta/epsilon/eta/theta types Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:B1H1I7 712
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations