ZFIN ID: ZDB-GENE-080327-34
Gene Name: cell adhesion molecule 1b
Gene Symbol: cadm1b    Nomenclature History

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Previous Name: sc:d0664

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have cholesterol 24-hydroxylase activity and heme binding activity. Involved in glial cell development and retina development in camera-type eye. Predicted to localize to integral component of membrane. Is expressed in cleithrum; immature eye; and nervous system. Human ortholog(s) of this gene implicated in breast carcinoma and prostate cancer. Orthologous to human CADM1 (cell adhesion molecule 1).
Genome Resources: Alliance (1),  Gene:562183 (1),  Ensembl(GRCz11):ENSDARG00000042677 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10395 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cadm1b
    1
    CRISPR2-cadm1b
    1
    DISEASE ASSOCIATED WITH cadm1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cadm1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glial cell development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function cholesterol 24-hydroxylase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cadm1b-201 (1)    Ensembl 2332
    ncRNA cadm1b-002 (1)    Ensembl 952
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cadm1b No data available
    MARKER RELATIONSHIPS
    cadm1b Contained in: [BAC] DKEY-71G12 (order this)
    cadm1b Encodes: [EST] cssl:d0664 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001113552 (1) 1268 nt
    Genomic GenBank:CR848835 (1) 216994 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B0F6R1 (1) 411 aa
    Sequence Information (all 18)
    ORTHOLOGY for cadm1b ( Chr: 15 )
    CITATIONS (24)