ZFIN ID: ZDB-GENE-080327-21
Gene Name: extracellular leucine-rich repeat and fibronectin type III domain containing 1b
Gene Symbol: elfn1b    Nomenclature History

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Previous Names: elfn1 (1), sc:d0369

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to localize to extracellular matrix and extracellular space. Is expressed in brain and neurons. Used to study schizophrenia. Orthologous to human ELFN1 (extracellular leucine rich repeat and fibronectin type III domain containing 1).
Genome Resources: Alliance (1),  Gene:100144401 (1),  Ensembl(GRCz11):ENSDARG00000074372 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a217 Complex Unknown Unknown CRISPR
sa78 Point Mutation Unknown Unknown ENU
sa89 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10220 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14916 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39553 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-elfn1b 1
    CRISPR2-elfn1b 1
    CRISPR3-elfn1b 1
    CRISPR4-elfn1b 1
    DISEASE ASSOCIATED WITH elfn1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH elfn1b VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    schizophrenia elfn1ba217/a217 standard conditions Thyme et al., 2019
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component integral component of membrane (more)
    Molecular Function protein binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA elfn1b-201 (1)    Ensembl 4282
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM elfn1b No data available
    MARKER RELATIONSHIPS
    elfn1b Contained in: [BAC] CH211-65G16 (1), DKEY-232D5 (1) (order this)
    elfn1b Encodes: [EST] cssl:d0369 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_001920348 (1) 3225 nt
    Genomic GenBank:BX649473 (1) 167871 nt
    Select Tool
    Polypeptide UniProtKB:F1Q7Y5 (1) 814 aa
    Sequence Information (all 14)
    ORTHOLOGY for elfn1b ( Chr: 1 )
    CITATIONS (26)