ZFIN ID: ZDB-GENE-080327-16
Gene Name: leucine rich repeat and Ig domain containing 1a
Gene Symbol: lingo1a    Nomenclature History

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Previous Name: sc:d0342

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have epidermal growth factor receptor binding activity. Involved in axon regeneration. Predicted to localize to extracellular matrix and extracellular space. Is expressed in basal plate midbrain region; immature eye; and nervous system. Human ortholog(s) of this gene implicated in glaucoma. Orthologous to human LINGO1 (leucine rich repeat and Ig domain containing 1).
Genome Resources: Alliance (1),  Gene:564943 (1),  Ensembl(GRCz11):ENSDARG00000034165 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-lingo1a N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH lingo1a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mental retardation, autosomal recessive 64 618103
DISEASE ASSOCIATED WITH lingo1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process axon regeneration (more)
Cellular Component integral component of membrane (more)
Molecular Function protein binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA lingo1a-202 (1)    Ensembl 1860
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM lingo1a No data available
MARKER RELATIONSHIPS
lingo1a Contained in: [BAC] CH211-107D11 (1), DKEY-7N16 (1) (order this)
lingo1a Encodes: [EST] cssl:d0342 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_005174270 (1) 4534 nt
Genomic GenBank:BX005076 (1) 207084 nt Blast at MegaBLAST
Polypeptide UniProtKB:F8W4D7 (1) 619 aa
Sequence Information (all 19)
ORTHOLOGY for lingo1a ( Chr: 25 )
CITATIONS (23)