ZFIN ID: ZDB-GENE-080320-2
Gene Name: calcium channel, voltage-dependent, beta 4a subunit
Gene Symbol: cacnb4a

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Attributions

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Previous Names: CAB4a (1), cacnb4.2 (1)

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
  atrium, blastoderm, brain, cerebellum (all 27) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa34703 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-cacnb4a (1)
    PHENOTYPE
    Data: 2 figures from Ebert et al., 2008
    Observed in: central nervous system, epiboly involved in gastrulation with mouth forming second, marginal blastomere, whole organism (all 5) expand
    DISEASE ASSOCIATED WITH cacnb4a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    episodic ataxia type 5 Episodic ataxia, type 5 613855
    idiopathic generalized epilepsy {Epilepsy, idiopathic generalized, susceptibility to, 9} 607682
    {Epilepsy, juvenile myoclonic, susceptibility to, 6} 607682
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process epiboly involved in gastrulation with mouth forming second (more)
    Cellular Component voltage-gated calcium channel complex (more)
    Molecular Function voltage-gated calcium channel activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000584 (1)
  • InterPro:IPR001452 (1)
  • InterPro:IPR008079 (1)
  • InterPro:IPR008145 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS50002 (1)
  • Pfam:PF00625 (1)
  • Pfam:PF12052 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cacnb4a-001 (1) 1568
    cacnb4a-002 (1) 1497
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cacnb4a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cacnb4aContained in: [BAC] DKEY-219C10 (order this)
    cacnb4aEncodes: [cDNA] MGC:198320 (1) (order this), MGC:198324 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001113519 (1) 2446bp
    Genomic GenBank:BX548038 (1) 173526bp
    Select Tool
    Polypeptide UniProtKB:B0F0D0 (1) 519aa
    Sequence Clusters UniGene:116506 (1)
    Sequence Information (all 25)
    OTHER cacnb4a GENE PAGES
  • Gene:562422 (1)
  • VEGA:OTTDARG00000025898 (1)
  • Ensembl(GRCz10):ENSDARG00000009738 (1)
  • ORTHOLOGY for cacnb4a (Chr: 9)
    Species Symbol Chromosome Accession # Evidence
    Human CACNB4 2
  • Gene:785
  • OMIM:601949
  • HGNC:1404
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (3)
    Mouse Cacnb4 2
  • MGI:103301
  • Gene:12298
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    Download Curated Orthology
    CITATIONS (16)