Gene

jam2b

ID

ZDB-GENE-080229-3

Name

junctional adhesion molecule 2b

Symbol

jam2b Nomenclature History

Previous Names

jamb2 (1)
im:7155552 (1)
sc:d0813 (1)
si:ch211-160b11.5

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Is expressed in several structures, including mesoderm; musculature system; pectoral fin bud; pharyngeal arch; and ventral mesenchyme. Orthologous to human JAM2 (junctional adhesion molecule 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7155552 (31 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With jam2b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Basal ganglia calcification, idiopathic, 8, autosomal recessive	618824

Associated With jam2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR042625	Junctional adhesion molecule B
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily