Gene
sc:d0202
- ID
- ZDB-GENE-080226-9
- Name
- sc:d0202
- Symbol
- sc:d0202 Nomenclature History
- Previous Names
-
- icam1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable integrin binding activity. Predicted to act upstream of or within cell-cell adhesion. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); biliary atresia; diabetic retinopathy; inflammatory bowel disease (multiple); and uveitis (multiple). Orthologous to human ICAM1 (intercellular adhesion molecule 1) and ICAM4 (intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d202 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR003987 | Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR013768 | Intercellular adhesion molecule, N-terminal |
| Family | IPR047012 | Intercellular adhesion molecule/vascular cell adhesion molecule |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Intercellular adhesion molecule, N-terminal | Intercellular adhesion molecule/vascular cell adhesion molecule | Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32THW5 | InterPro | 302 | |||||||||
| UniProtKB:X1WFG6 | InterPro | 292 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sc:d0202-201
(1)
|
Ensembl | 1,387 nt |
Interactions and Pathways
No data available
Plasmids
No data available