Gene

fmn2b

ID
ZDB-GENE-080225-35
Name
formin 2b
Symbol
fmn2b Nomenclature History
Previous Names
  • im:7158925
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have microtubule binding activity. Predicted to be involved in formin-nucleated actin cable assembly and intracellular transport. Predicted to localize to cytoplasm; endoplasmic reticulum membrane; and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in central nervous system. Orthologous to human FMN2 (formin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Nagar et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fmn2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive intellectual developmental disorder 47 Alliance Intellectual developmental disorder, autosomal recessive 47 616193
Associated With fmn2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR015425 Formin, FH2 domain
Family IPR001265 Formin homology family, Cappuccino subfamily
Homologous_superfamily IPR042201 Formin, FH2 domain superfamily
Domain Details Per Protein
Protein Length Formin, FH2 domain Formin, FH2 domain superfamily Formin homology family, Cappuccino subfamily
UniProtKB:A0A2R8QAK8 1479
UniProtKB:A0A8M3B7Q6 1473
UniProtKB:A0A8M3AYR9 869
UniProtKB:A0A8M3B4X8 1460
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations