Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-080225-11
Gene Name: Wolfram syndrome 1a (wolframin)
Gene Symbol: wfs1a
Previous Names: wfs1, im:7153058 (1), si:dkey-228b21.2
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (5 images) from Thisse et al., 2004 [IMAGE:7153058]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
  myotome
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa10021, sa11465
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Deafness, autosomal dominant 6/14/38 600965
Wolfram syndrome 222300
Wolfram-like syndrome, autosomal dominant 614296
?Cataract 41 116400
{Diabetes mellitus, noninsulin-dependent, association with} 125853
GENE ONTOLOGY
Ontology GO Term
Biological Process biological_process (more)
Cellular Component cellular_component (more)
Molecular Function molecular_function (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
 Withdrawn Transcriptsextinct
GENE PRODUCT DESCRIPTION No description available
ANTIBODIES No data available
CONSTRUCTS WITH SEQUENCES FROM wfs1a No data available
SEGMENT (CLONE AND PROBE) RELATIONSHIPS
wfs1a Contained in: [BAC] DKEY-228B21 (1)
wfs1a Encodes: [EST] IMAGE:7153058 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_690160 (1) 3801 bp
Genomic GenBank:BX530018 (1) 221617 bp Blast at MegaBLAST
Polypeptide RefSeq:XP_695252 (1) 1061 aa
Sequence Clusters UniGene:88234 (1)
Sequence Information (all 12)
OTHER wfs1a GENE PAGES
  • Gene:566876 (1)
  • MAPPING INFORMATION
    Chr: Unknown Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish wfs1a  
    Human WFS1 4 (4p16.1)
  • OMIM:606201
  • Gene:7466
  • Mouse Wfs1 5 ( 19.46 cM)
  • MGI:1328355
  • Gene:22393
  • CITATIONS (9)