ZFIN ID: ZDB-GENE-080219-36
Gene Name: potassium voltage-gated channel, shaker-related subfamily, beta member 2 b
Gene Symbol: kcnab2b    Nomenclature History

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Previous Name: zgc:171453

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have voltage-gated potassium channel activity. Involved in regulation of action potential and regulation of transmission of nerve impulse. Predicted to localize to the cytoplasm and integral component of membrane. Is expressed in Mauthner neurons. Orthologous to human KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2).
Genome Resources: Alliance (1),  Gene:565014 (1),  Ensembl(GRCz11):ENSDARG00000062134 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24307 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37682 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-kcnab2b N/A 1
    MO2-kcnab2b N/A 1
    DISEASE ASSOCIATED WITH kcnab2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH kcnab2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of action potential (more)
    Cellular Component cytoplasm (more)
    Molecular Function voltage-gated potassium channel activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related
    Family IPR005400 Potassium channel, voltage-dependent, beta subunit, KCNAB1
    Family IPR005983 Potassium channel, voltage-dependent, beta subunit, KCNAB
    Domain IPR023210 NADP-dependent oxidoreductase domain
    Homologous_superfamily IPR036812 NADP-dependent oxidoreductase domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript kcnab2b-201 (1)    Ensembl 1787
    mRNA kcnab2b-202 (1)    Ensembl 1239
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM kcnab2b No data available
    MARKER RELATIONSHIPS
    kcnab2b Contained in: [BAC] DKEY-25B23 (1) (order this)
    kcnab2b Encodes: [cDNA] MGC:171453 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001328419 (1)
    Genomic GenBank:CR354562 (1) 201764 bp Blast at MegaBLAST
    Polypeptide UniProtKB:E9QGU5 (1) 412 aa
    Sequence Information (all 24)
    ORTHOLOGY for kcnab2b ( Chr: 23 )
    CITATIONS (15)