ZFIN ID: ZDB-GENE-080219-32
Gene Name: protein phosphatase 4, catalytic subunit b
Gene Symbol: ppp4cb    Nomenclature History

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Previous Name: zgc:172126

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity and phosphoprotein phosphatase activity. Involved in determination of ventral identity and positive regulation of BMP signaling pathway. Predicted to localize to cytoplasm and microtubule organizing center. Is expressed in blastoderm; fertilized egg; and head. Orthologous to human PPP4C (protein phosphatase 4 catalytic subunit).
Genome Resources: Alliance (1),  Gene:562705 (1),  Ensembl(GRCz11):ENSDARG00000076439 (2)
GENE EXPRESSION
All Expression Data: Fig. 1 from Jia et al., 2012
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1713 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11029 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19020 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ppp4cb N/A 1
    MO2-ppp4cb N/A 1
    DISEASE ASSOCIATED WITH ppp4cb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ppp4cb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal/ventral pattern formation (more)
    Cellular Component cytoplasm (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ppp4cb-201 (1)    Ensembl 1979
    ppp4cb-202 (1)    Ensembl 664
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ppp4cb No data available
    MARKER RELATIONSHIPS
    ppp4cb Contained in: [BAC] CH211-136M16 (1)
    ppp4cb Encodes: [cDNA] MGC:172126 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001111168 (1) 1944 nt
    Genomic GenBank:AL929495 (1) 157568 nt
    Select Tool
    Polypeptide UniProtKB:A9JRC7 (1) 307 aa
    Sequence Information (all 12)
    ORTHOLOGY for ppp4cb ( Chr: 12 )
    CITATIONS (27)