ZFIN ID: ZDB-GENE-080219-19
Gene Name: unc-5 netrin receptor A
Gene Symbol: unc5a    Nomenclature History

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Previous Name: zgc:175190 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have netrin receptor activity. Predicted to be involved in anterior/posterior axon guidance. Predicted to localize to the integral component of membrane. Is expressed in brain; eye; and trunk. Orthologous to human UNC5A (unc-5 netrin receptor A).
Genome Resources: Alliance (1),  Gene:799734 (1),  Ensembl(GRCz11):ENSDARG00000099034 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019083Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la019084Tg Transgenic Insertion Unknown Unknown DNA
    sa22555 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH unc5a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH unc5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process netrin-activated signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function netrin receptor activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000488 Death domain
    Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
    Domain IPR000906 ZU5 domain
    Domain IPR003598 Immunoglobulin subtype 2
    Domain IPR003599 Immunoglobulin subtype
    Domain IPR007110 Immunoglobulin-like domain
    Homologous_superfamily IPR011029 Death-like domain superfamily
    Domain IPR013098 Immunoglobulin I-set
    Homologous_superfamily IPR013783 Immunoglobulin-like fold
    Domain IPR033772 UPA domain
    Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
    Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
    Family IPR037936 Netrin receptor UNC5
    Domain IPR042155 UNC5A, death domain
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM unc5a No data available
    MARKER RELATIONSHIPS
    unc5a Encodes: [cDNA] MGC:175190 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001114465 (1) 3468 bp
    Genomic GenBank:CABZ01070350 (1) 23945 bp
    Polypeptide UniProtKB:A9JRY6 (1) 860 aa
    Sequence Information (all 70)
    ORTHOLOGY for unc5a ( Chr: 14 )
    CITATIONS (21)