Gene
htra2-14
- ID
- ZDB-GENE-080215-8
- Name
- HtrA serine peptidase 2-14
- Symbol
- htra2-14 Nomenclature History
- Previous Names
-
- htra2-13
- zgc:174193
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable serine-type endopeptidase activity. Predicted to be involved in mitochondrion organization; positive regulation of apoptotic process; and programmed cell death. Predicted to act upstream of or within proteolysis. Predicted to be located in mitochondrial intermembrane space and mitochondrial membrane. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 8; Parkinson's disease; and motor neuron disease. Orthologous to human HTRA2 (HtrA serine peptidase 2).
- Genome Resources
-
- Alliance (1)
- Gene:560917 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | PDZ domain | PDZ domain 6 | PDZ superfamily | Peptidase S1C | Peptidase S1, PA clan | Serine proteases, trypsin domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32TN53 | InterPro | 194 | ||||||
| UniProtKB:A0AB32U3M2 | InterPro | 308 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance