ZFIN ID: ZDB-GENE-080204-89
Gene Name: potassium voltage-gated channel, shaker-related subfamily, member 2b
Gene Symbol: kcna2b    Nomenclature History

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Previous Name: zgc:174907

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to localize to axon; dendrite; and voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 32. Orthologous to human KCNA2 (potassium voltage-gated channel subfamily A member 2).
Genome Resources: Alliance (1),  Gene:562853 (1),  Ensembl(GRCz11):ENSDARG00000102064 (1)
GENE EXPRESSION
All Expression Data: Fig. 6 from Watanabe et al., 2014
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7308 Point Mutation Unknown Premature Stop ENU
sa39393 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH kcna2b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    early infantile epileptic encephalopathy 32 Alliance Epileptic encephalopathy, early infantile, 32 616366
    DISEASE ASSOCIATED WITH kcna2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ion transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ion channel activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM kcna2b No data available
    MARKER RELATIONSHIPS
    kcna2b Encodes: [cDNA] MGC:174907 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001111170 (1) 2852 nt
    Genomic GenBank:FO904981 (1) 32781 nt
    Select Tool
    Polypeptide UniProtKB:A9JTD2 (1) 495 aa
    Sequence Information (all 17)
    ORTHOLOGY for kcna2b ( Chr: 23 )
    CITATIONS (18)