ZFIN ID: ZDB-GENE-080204-85
Gene Name: carbonic anhydrase IV a
Gene Symbol: ca4a    Nomenclature History

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Previous Names: zCA4a (1), zgc:171842

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to localize to plasma membrane. Is expressed in brain; eye; heart; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 17. Orthologous to human CA4 (carbonic anhydrase 4).
Genome Resources: Alliance (1),  Gene:555196 (1),  Ensembl(GRCz11):ENSDARG00000043589 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa477 Point Mutation Unknown Premature Stop ENU
sa12682 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20331 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ca4a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    retinitis pigmentosa 17 Alliance Retinitis pigmentosa 17 600852
    DISEASE ASSOCIATED WITH ca4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process one-carbon metabolic process (more)
    Cellular Component anchored component of membrane (more)
    Molecular Function carbonate dehydratase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ca4a No data available
    MARKER RELATIONSHIPS
    ca4a Encodes: [cDNA] MGC:171842 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001114407 (1) 2661 nt
    Genomic GenBank:FO680663 (1) 110962 nt
    Select Tool
    Polypeptide UniProtKB:A9JSU9 (1) 306 aa
    Sequence Information (all 10)
    ORTHOLOGY for ca4a ( Chr: 5 )
    CITATIONS (24)