ZFIN ID: ZDB-GENE-080204-8
Gene Name: membrane-associated ring finger (C3HC4) 8
Gene Symbol: march8    Nomenclature History

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Previous Name: zgc:171495

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have MHC protein binding activity and ubiquitin protein ligase activity. Involved in protein ubiquitination. Predicted to localize to early endosome membrane; late endosome membrane; and lysosome. Is expressed in blastomere and brain. Orthologous to human MARCHF8 (membrane associated ring-CH-type finger 8).
Genome Resources: Alliance (1),  Gene:567818 (1),  Ensembl(GRCz11):ENSDARG00000062489 (2)
GENE EXPRESSION
All Expression Data: Fig. S2 from Kim et al., 2014
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-march8 N/A 1
DISEASE ASSOCIATED WITH march8 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH march8 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process protein ubiquitination (more)
Cellular Component integral component of membrane (more)
Molecular Function zinc ion binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA march8-201 (1)    Ensembl 1439
march8-202 (1)    Ensembl 891
march8-204 (1)    Ensembl 977
ncRNA march8-003 (1)    Ensembl 732
march8-005 (1)    Ensembl 539
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM march8 No data available
MARKER RELATIONSHIPS
march8 Contained in: [BAC] CH211-214N2 (1), DKEY-27M7 (1) (order this), DKEY-74C10 (1) (order this)
march8 Encodes: [cDNA] MGC:171495 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001111193 (1) 1441 nt
Genomic GenBank:BX470214 (1) 234545 nt Blast at MegaBLAST
Polypeptide UniProtKB:A0A286YAB5 (1) 580 aa
Sequence Information (all 29)
ORTHOLOGY for march8 ( Chr: 13 )
CITATIONS (17)